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Cover Picture: Asymmetric Organocatalytic Domino Reactions (Angew. Chem. Int. Ed. 10/2007)
Author(s) -
Enders Dieter,
Grondal Christoph,
Hüttl Matthias R. M.
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200790031
Subject(s) - domino , cover (algebra) , organocatalysis , catalysis , domino effect , chemistry , cascade reaction , reaction conditions , int , enantioselective synthesis , organic chemistry , computer science , physics , mechanical engineering , engineering , operating system , nuclear physics
A gentle nudge is all it takes to set off a line of dominoes, and the same principle applies to domino reactions with a suitable catalyst as initiator. Just as dominoes fall down sequentially, the intermediate compounds in a domino reaction react successively under the same reaction conditions to give the desired product. Thus, complex structures can often be constructed from simple precursors, as D. Enders et al. describe in their Minireview on page 1570 ff. on asymmetric organocatalytic domino reactions.