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Cover Picture: Total Synthesis of Paliurine F (Angew. Chem. Int. Ed. 4/2007)
Author(s) -
Toumi Mathieu,
Couty François,
Evano Gwilherm
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200790000
Subject(s) - cover (algebra) , int , total synthesis , stereochemistry , chemistry , combinatorial chemistry , computer science , engineering , programming language , mechanical engineering
The sedative paliurine F , which was isolated from the roots of Paliurus ramossisimus , is part of a huge family of natural products that display interesting biological effects and possess an especially appealing and challenging macrocyclic structure. In their Communication on page 572 ff., G. Evano and co‐workers describe the synthesis of one of these cyclopeptide alkaloids, paliurine F, using a route that showcases the recent advances in copper(I)‐mediated coupling reactions.