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Periodic Iron Nanomineralization in Human Serum Transferrin Fibrils
Author(s) -
Ghosh Surajit,
Mukherjee Arindam,
Sadler Peter J.,
Verma Sandeep
Publication year - 2008
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200705723
Subject(s) - transferrin , fibril , chemistry , biophysics , biochemistry , biology
Spotty iron : Surface deposition of holo human transferrin from aqueous solutions gives rise to long protein fibrils with regular periodic nanomineralization along their length of an Fe III oxide/hydroxide closely resembling lepidocrocite (γ‐FeO(OH)). Such a new role for this serum protein could have important biological and medical implications.