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Water‐Soluble Monofunctional Perylene and Terrylene Dyes: Powerful Labels for Single‐Enzyme Tracking
Author(s) -
Peneva Kalina,
Mihov Gueorgui,
Nolde Fabian,
Rocha Susana,
Hotta Junichi,
Braeckmans Kevin,
Hofkens Johan,
Ujii Hiroshi,
Herrmann Andreas,
Müllen Klaus
Publication year - 2008
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200705409
Subject(s) - perylene , fluorescence , biomolecule , covalent bond , enzyme , chemistry , substrate (aquarium) , molecule , photochemistry , tracking (education) , biochemistry , organic chemistry , biology , ecology , physics , quantum mechanics , psychology , pedagogy
All in one : Exceptionally photostable, highly fluorescent, water‐soluble, and monofunctional perylene and terrylene dyes bearing reactive groups for covalent attachment to biomolecules have been synthesized (see picture). Single‐molecule enzyme tracking revealed that single enzymes could be visualized even on a substrate with fluorescent background.