Spectroscopically Enhancing Electrical Nanotraps | Zendy

Zheng Gengfeng | Zendy; Qin Lidong | Zendy; Mirkin Chad A. | Zendy

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Spectroscopically Enhancing Electrical Nanotraps

Author(s) -

Zheng Gengfeng,

Qin Lidong,

Mirkin Chad A.

Publication year - 2008

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.200705312

Subject(s) - raman spectroscopy , microfluidics , nanotechnology , lithography , oligonucleotide , sample (material) , nanometre , materials science , analytical chemistry (journal) , chemistry , optoelectronics , physics , dna , optics , environmental chemistry , chromatography , biochemistry , composite material

Electrical traps with Raman hot spots : On‐wire‐lithography (OWL) nanotraps electrically localize DNA in a nanometer‐scale gap (see picture, red oligonucleotides with Raman dyes), which allows for the identification of the localized material by surface‐enhanced Raman spectroscopy. With microfluidic delivery, sample volumes as small as 1 μL with target concentrations as low as 230 f M can be studied without secondary amplification.

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