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Bacterial Biosynthesis of a Multipotent Stilbene
Author(s) -
Joyce Susan A.,
Brachmann Alexander O.,
Glazer Itamar,
Lango Lea,
Schwär Gertrud,
Clarke David J.,
Bode Helge B.
Publication year - 2008
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200705148
Subject(s) - biosynthesis , photorhabdus , bacteria , biology , gene , microbiology and biotechnology , chemistry , biochemistry , genetics
Commuting between kingdoms : The biosynthesis of the only nonplant stilbene 1 from Photorhabdus bacteria has been solved by identification of all the genes involved in its biosynthesis and by feeding experiments. Stilbene 1 is derived from the condensation of two β‐ketoacyl thioesters and is required for the normal development of Heterorhabditis nematodes, the natural host of Photorhabdus.