Premium
Highly Efficient Catalyst Systems Using Iron Complexes with a Tetradentate PNNP Ligand for the Asymmetric Hydrogenation of Polar Bonds
Author(s) -
SuiSeng Christine,
Freutel Friederike,
Lough Alan J.,
Morris Robert H.
Publication year - 2008
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200705115
Subject(s) - ruthenium , transfer hydrogenation , catalysis , ligand (biochemistry) , chemistry , polar , combinatorial chemistry , asymmetric hydrogenation , polymer chemistry , organic chemistry , enantioselective synthesis , physics , receptor , biochemistry , astronomy
Iron competes with pricey ruthenium : The first catalyst systems using iron complexes for asymmetric H 2 hydrogenation at 50 °C and asymmetric transfer hydrogenation at room temperature has been discovered. The transfer hydrogenation activity is similar to that of the best ruthenium catalyst. Surprisingly, the precatalysts have a tetradentate diiminodiphosphine ligand which has no NH functionality.