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Ditryptophan Conjugation Triggers Conversion of Biotin Fibers into Soft Spherical Structures
Author(s) -
Joshi K. B.,
Verma Sandeep
Publication year - 2008
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200705012
Subject(s) - biotin , dipeptide , simple (philosophy) , chemistry , morphogenesis , combinatorial chemistry , computer science , nanotechnology , amino acid , polymer science , materials science , biochemistry , philosophy , gene , epistemology
Trigger happy : Biotin and its methyl ester form long fibers in solution, which are transformed into soft spherical structures upon simple conjugation with ditryptophan dipeptide (see picture). Such morphogenesis is not achieved in a controlled fashion by other aromatic amino acids.