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High‐Throughput, Real‐Time Monitoring of the Self‐Assembly of DNA Nanostructures by FRET Spectroscopy
Author(s) -
Saccà Barbara,
Meyer Rebecca,
Feldkamp Udo,
Schroeder Hendrik,
Niemeyer Christof M.
Publication year - 2008
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200704836
Subject(s) - förster resonance energy transfer , throughput , tile , spectroscopy , characterization (materials science) , fluorescence spectroscopy , nanotechnology , nanostructure , dna , computer science , fluorescence , chemistry , computational biology , materials science , physics , biology , telecommunications , optics , biochemistry , composite material , quantum mechanics , wireless
Tiles and arrays : The self‐assembly of DNA nanostructures can be monitored in real time and with high throughput by FRET spectroscopy. A van't Hoff analysis of the fluorescence data allows for a complete thermodynamic characterization of the tile formation as well as array formation (see picture).