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Total Synthesis and Structure Assignment of the Anthrone C‐Glycoside Cassialoin
Author(s) -
Koyama Yasuhito,
Yamaguchi Ryo,
Suzuki Keisuke
Publication year - 2008
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200704625
Subject(s) - anthrone , stereocenter , retrosynthetic analysis , intramolecular force , stereochemistry , glycoside , isoxazole , chemistry , total synthesis , organic chemistry , enantioselective synthesis , catalysis
Configuration confirmed : The first total synthesis and structure assignment of the anthrone C‐glycoside cassialoin ( 1 ) have been achieved by exploiting an isoxazole‐containing stereogenic α‐ketol and a subsequent intramolecular redox reaction (see retrosynthetic analysis; MOM = methoxymethyl).