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Electrically Addressable Cell Immobilization Using Phenylboronic Acid Diazonium Salts
Author(s) -
Polsky Ronen,
Harper Jason C.,
Wheeler David R.,
Arango Dulce C.,
Brozik Susan M.
Publication year - 2008
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200704597
Subject(s) - phenylboronic acid , yeast , chemistry , on demand , cell , scheme (mathematics) , saccharomyces cerevisiae , computer science , combinatorial chemistry , nanotechnology , biochemistry , materials science , catalysis , mathematics , multimedia , mathematical analysis
Holding cells : Individual gold electrodes can be activated by phenylboronic acid diazonium salts for the facile and reversible immobilization of eukaryotic cells (see scheme). This platform provides a simple method for on‐demand release of captured cells (yeast and macrophage) and can be used in single‐cell or array‐based studies.