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Fluorescent Molecular Logic Gates Using Microfluidic Devices
Author(s) -
Kou Songzi,
Lee Han Na,
van Noort Danny,
Swamy K. M. K.,
Kim So Hyun,
Soh Jung Hyun,
Lee KangMu,
Nam SeongWon,
Yoon Juyoung,
Park Sungsu
Publication year - 2008
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200703813
Subject(s) - microfluidics , fluorescence , logic gate , and gate , rhodamine , metal ions in aqueous solution , nanotechnology , computer science , fluorescein , chemistry , ion , materials science , physics , algorithm , organic chemistry , optics
Starting gate : A molecular logic gate is based on chemosensors that change their fluorescence intensity in response to various inputs (pH, metal ions) in a microfluidic system. A combinatorial circuit, such as a half adder (see picture), uses fluorescein (green) and rhodamine B (red) derivatives that respond to pH. A logic gate with a protein and Cu 2+ ions as inputs is also described.
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