Chemical Synthesis of the GHIJK Ring System and Further Experimental Support for the Originally Assigned Structure of Maitotoxin | Zendy

Nicolaou K. C. | Zendy; Cole Kevin P. | Zendy; Frederick Michael O. | Zendy; Aversa Robert J. | Zendy; Denton Ross M. | Zendy

Premium

Chemical Synthesis of the GHIJK Ring System and Further Experimental Support for the Originally Assigned Structure of Maitotoxin

Author(s) -

Nicolaou K. C.,

Cole Kevin P.,

Frederick Michael O.,

Aversa Robert J.,

Denton Ross M.

Publication year - 2007

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.200703742

Subject(s) - ring (chemistry) , chemistry , stereochemistry , marine toxin , molecule , computational chemistry , organic chemistry , biochemistry , toxin

Accepting the proposal : The originally proposed structure of maitotoxin has recently come under scrutiny based on biosynthetic and computational considerations. A newly synthesized ring framework corresponding to the GHIJK ring domain (see structure) of the molecule provided, through 13 C NMR spectroscopic comparisons, strong experimental support for the originally proposed structure.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research