Kinetic Resolution of 1,2‐Diols through Highly Site‐ and Enantioselective Catalytic Silylation | Zendy

Zhao Yu | Zendy; Mitra Aurpon W. | Zendy; Hoveyda Amir H. | Zendy; Snapper Marc L. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Kinetic Resolution of 1,2‐Diols through Highly Site‐ and Enantioselective Catalytic Silylation

Author(s) -

Zhao Yu,

Mitra Aurpon W.,

Hoveyda Amir H.,

Snapper Marc L.

Publication year - 2007

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.200703650

Subject(s) - enantioselective synthesis , dihydroxylation , kinetic resolution , silylation , catalysis , enantiomer , chemistry , substrate (aquarium) , organic chemistry , combinatorial chemistry , stereochemistry , biology , ecology

Resolved to silylate : A chiral silylation catalyst is used for kinetic resolution of three classes of acyclic 1,2‐diols. The catalyst differentiates, with excellent precision, between the two hydroxy groups of a substrate. The majority of the diols, obtained in high enantiomeric purity, cannot be accessed with similar stereochemical purity through catalytic asymmetric dihydroxylation.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research