Multifunctional Magneto‐Polymeric Nanohybrids for Targeted Detection and Synergistic Therapeutic Effects on Breast Cancer | Zendy

Yang Jaemoon | Zendy; Lee ChoongHwan | Zendy; Ko HyunJu | Zendy; Suh JinSuck | Zendy; Yoon HoGeun | Zendy; Lee Kwangyeol | Zendy; Huh YongMin | Zendy; Haam Seungjoo | Zendy

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Multifunctional Magneto‐Polymeric Nanohybrids for Targeted Detection and Synergistic Therapeutic Effects on Breast Cancer

Author(s) -

Yang Jaemoon,

Lee ChoongHwan,

Ko HyunJu,

Suh JinSuck,

Yoon HoGeun,

Lee Kwangyeol,

Huh YongMin,

Haam Seungjoo

Publication year - 2007

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.200703554

Subject(s) - amphiphile , copolymer , breast cancer , materials science , cancer , nanotechnology , magneto , cancer research , biomedical engineering , medicine , chemistry , polymer , organic chemistry , composite material , combustion

Diagnosis and treatment all in one : Multifunctional magneto‐polymeric nanohybrids (MMPNs) have been synthesized using ultrasensitive MnFe 2 O 4 nanocrystals, chemotherapeutic agents, and encapsulating amphiphilic block copolymers for targeted detection by MRI and treatment of breast cancer. See the TEM image (left) of an MMPN and T 2 ‐weighted MR images (top row) and color map (bottom row) of the relaxivity R 2 for NIH3T6.7 and MDA‐MB‐231 cells.

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