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Tandem Catalysis for a One‐Pot Regioselective Protection of Carbohydrates: The Example of Glucose
Author(s) -
Français Antoine,
Urban Dominique,
Beau JeanMarie
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200703437
Subject(s) - tandem , regioselectivity , trisaccharide , catalysis , chemistry , combinatorial chemistry , computer science , process (computing) , reaction conditions , organic chemistry , engineering , operating system , aerospace engineering
Fine‐tuning the conditions for a tandem reaction using a single catalyst in a single reaction vessel leads to carbohydrate building blocks displaying different patterns of protecting groups (see picture). This process greatly simplifies the access to oligomers, as illustrated by the rapid assembly of a trisaccharide.