Premium
“Homeopathic” Catalytic Activity and Atom‐Leaching Mechanism in Miyaura–Suzuki Reactions under Ambient Conditions with Precise Dendrimer‐Stabilized Pd Nanoparticles
Author(s) -
Diallo Abdou Khadri,
Ornelas Cátia,
Salmon Lionel,
Ruiz Aranzaes Jaime,
Astruc Didier
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200703067
Subject(s) - catalysis , chemistry , dendrimer , leaching (pedology) , nanoparticle , atom (system on chip) , medicinal chemistry , extraction (chemistry) , combinatorial chemistry , nuclear chemistry , polymer chemistry , organic chemistry , nanotechnology , materials science , computer science , soil water , environmental science , soil science , embedded system
What generation gap? Three generations (G 0 , G 1 , G 2 ) of dendrimer‐stabilized Pd nanoparticles (PdNPs) synthesized by click chemistry catalyze Suzuki reactions of PhX (X=I or Br) at 25 °C with increasing catalytic activity as their concentration is decreased: A turnover number of 540 000 was observed for the G 0 catalyst at 1 ppm in Pd atoms. Extraction of the PdNPs with alkanethiols yields robust Suzuki catalysts for PhI only (see scheme).