Premium
An Iron Catalyst for Ketone Hydrogenations under Mild Conditions
Author(s) -
Bullock R. Morris
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200703053
Subject(s) - chemoselectivity , ketone , catalysis , hydride , homogeneous , ionic liquid , noyori asymmetric hydrogenation , chemistry , metal , ionic bonding , homogeneous catalysis , organic chemistry , ruthenium , ion , physics , thermodynamics
Doing it on the cheap : An iron‐based homogeneous catalyst for ketone hydrogenation was reported, thus avoiding the use of a precious metal. Excellent yields and chemoselectivity for hydrogenation are found under mild conditions (25 °C, 3 atm H 2 ). An ionic hydrogenation mechanism allows the delivery of a proton from the OH group and a hydride from the metal center (see picture).