A General Method for the Direct α‐Arylation of Aldehydes with Aryl Bromides and Chlorides | Zendy

Martín Rubén | Zendy; Buchwald Stephen L. | Zendy

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A General Method for the Direct α‐Arylation of Aldehydes with Aryl Bromides and Chlorides

Author(s) -

Martín Rubén,

Buchwald Stephen L.

Publication year - 2007

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.200703009

Subject(s) - scope (computer science) , aryl , variety (cybernetics) , substitution (logic) , scheme (mathematics) , combinatorial chemistry , computer science , catalysis , chemistry , content (measure theory) , organic chemistry , mathematics , programming language , artificial intelligence , mathematical analysis , alkyl

Wide scope : A catalyst system able to efficiently perform the title reaction is described (see scheme). The high level of activity achieved allows for the synthesis of highly functionalized compounds with a wide variety of substitution patterns under very mild conditions.

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