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Electrochemical Aerobic Oxidation of Aminocyclopropanes to Endoperoxides
Author(s) -
Madelaine Claire,
Six Yvan,
Buriez Olivier
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200702903
Subject(s) - electrosynthesis , electrochemistry , autocatalysis , chemistry , catalysis , organic chemistry , electrode
Electrical synthesizer : Results of cyclic voltammetric studies on a range of aminocyclopropanes in the absence or in the presence of oxygen are in full agreement with the currently accepted autocatalytic mechanism for the aerobic oxidation of these compounds. A simple and efficient procedure was developed for the electrosynthesis of the corresponding endoperoxides (see scheme), some of which exhibit moderate antimalarial activity.