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Protecting‐Group‐Free Formal Synthesis of Platensimycin
Author(s) -
Tiefenbacher Konrad,
Mulzer Johann
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200702852
Subject(s) - protecting group , key (lock) , formal synthesis , chemistry , combinatorial chemistry , computer science , stereochemistry , organic chemistry , computer security , alkyl
Short cut : In a new approach to the recently discovered antibiotic platensimycin ( 1 ), Nicolaou's late key intermediate is synthesised without the use of protecting groups in five steps from a readily available starting material.