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Reply to “Recently Reported Crystalline Isothiazole Carbenes: Myth or Reality”
Author(s) -
Wolf Janine,
Böhlmann Winfried,
Findeisen Matthias,
Gelbrich Thomas,
Hofmann HansJörg,
Schulze Bärbel
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200702746
Subject(s) - isothiazole , mythology , chemistry , philosophy , photochemistry , medicinal chemistry , theology
In light of the results of Bertrand and co‐workers, the isothiazole carbenes previously reported by us cannot be considered to be stable. Evidently they are intermediates, which rapidly isomerize to the 2‐imino‐2 H ‐thiete isomers. Nevertheless, it is possible to obtain their dimers and to postulate their contribution in the formation of morpholino or piperidino derivatives.