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Enzyme‐Responsive Materials: Chirality to Program Polymer Reactivity
Author(s) -
Duxbury Christopher J.,
Hilker Iris,
de Wildeman Stefaan M. A.,
Heise Andreas
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200702438
Subject(s) - chirality (physics) , monomer , polymer , reactivity (psychology) , enzyme , chemistry , vinyl acetate , organic chemistry , combinatorial chemistry , polymer chemistry , materials science , copolymer , physics , medicine , chiral symmetry breaking , alternative medicine , pathology , quantum mechanics , nambu–jona lasinio model , quark
A programmed response : Enzyme‐responsive materials have been prepared from enzymatically synthesized, enantiomerically pure monomers. The extent of the material's response is encoded within its chiral makeup. This code can be effectively read out by an enzymatic process, which leads to a change in the thermal properties of the material. The picture shows esterification of chiral alcohol groups on a polymer backbone (green) with vinyl acetate (red).