Premium
A Practical Synthesis of the Phytosiderophore 2′‐Deoxymugineic Acid: A Key to the Mechanistic Study of Iron Acquisition by Graminaceous Plants
Author(s) -
Namba Kosuke,
Murata Yoshiko,
Horikawa Manabu,
Iwashita Takashi,
Kusumoto Shoichi
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200702403
Subject(s) - siderophore , transporter , mechanism (biology) , biochemistry , chemistry , computational biology , biology , gene , philosophy , epistemology
Ironing out plant uptake : The phytosiderophores mugineic acid (MA) and deoxymugineic acid (DMA) were synthesized in a few steps with minimum use of protecting groups and workup/purification procedures (see scheme; Boc: tert ‐butoxycarbonyl) and their potencies in transporter‐mediated iron(III) acquisition were tested. The sufficient supply of these compounds will enable study of the molecular mechanism of iron acquisition and utilization by graminaceous plants.