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Single‐Molecule Reactions in Liposomes
Author(s) -
Hsin TseMing,
Yeung Edward S.
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200702348
Subject(s) - liposome , electrofusion , fluorescence , chemistry , enzyme , substrate (aquarium) , molecule , biophysics , biochemistry , materials science , optics , biology , physics , organic chemistry , ecology , metallurgy
Solitary confinement : Single‐molecule reactions were initiated by trapping and fusing liposomes and monitored by fluorescence imaging. The pictures show: an optical image of the liposome containing the enzyme (A), a fluorescence image of one labeled enzyme molecule in the liposome (B), an optical image of the enzyme and substrate liposomes prior to electrofusion (C), an optical image of the fused liposome (D), and a fluorescence image of the fused liposome after incubation (E).