Premium
Tetrafluoro‐IBA and‐IBX: Hypervalent Iodine Reagents
Author(s) -
Richardson Robert D.,
Zayed Jameel M.,
Altermann Sabine,
Smith Daniel,
Wirth Thomas
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200702313
Subject(s) - hypervalent molecule , reagent , reactivity (psychology) , iodine , chemistry , catalysis , fluorine , organic chemistry , derivative (finance) , combinatorial chemistry , medicine , alternative medicine , pathology , financial economics , economics
Fluorine makes the difference : FIBX (see structure), the tetrafluoro derivative of the hypervalent iodine reagent, is more soluble and has higher reactivity than its nonfluorinated counterpart. An efficient synthesis of FIBX and initial reactions are presented. Some of these reactions can be conducted in standard organic solvents. Owing to the increased reactivity, new transformations and catalytic reactions may be possible.