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Iron‐Catalyzed Cross‐Coupling of Alkyl Halides with Alkenyl Grignard Reagents
Author(s) -
Guérinot Amandine,
Reymond Sébastien,
Cossy Janine
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200702206
Subject(s) - halide , alkyl , reagent , catalysis , chemistry , coupling reaction , coupling (piping) , grignard reagent , grignard reaction , medicinal chemistry , organic chemistry , polymer chemistry , combinatorial chemistry , materials science , metallurgy
Cheap and safe : An iron‐catalyzed cross‐coupling reaction between alkyl halides and alkenyl Grignard reagents is described. This CC bond coupling reaction is promoted by the cheap and nontoxic FeCl 3 and displays good tolerance against various functional groups.
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