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Lithiated Carbamates: Chiral Carbenoids for Iterative Homologation of Boranes and Boronic Esters
Author(s) -
Stymiest Jake L.,
Dutheuil Guillaume,
Mahmood Adeem,
Aggarwal Varinder K.
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200702146
Subject(s) - boranes , organic chemistry , chemistry , combinatorial chemistry , boron
Take your pick : Either enantiomer of either diastereomer of substrates bearing adjacent stereogenic centers is accessible through reaction of an ( R )‐ or ( S )‐lithiated carbamate with an ( R )‐ or ( S )‐boronic ester (see scheme; pin=pinacolate, OCb=substituted carbamate).
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