Premium
Rapid Patterning of Cells and Cell Co‐Cultures on Surfaces with Spatial and Temporal Control through Centrifugation
Author(s) -
Barrett Devin G.,
Yousaf Muhammad N.
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200701841
Subject(s) - polydimethylsiloxane , centrifugation , monolayer , nanotechnology , soft lithography , membrane , materials science , self assembled monolayer , cell , biophysics , chemistry , microcontact printing , lithography , biology , chromatography , optoelectronics , biochemistry , medicine , alternative medicine , pathology , fabrication
Cultural events : A methodology that combines surface chemistry with soft lithography and centrifugation allows the rapid, inexpensive, and complete patterning of cells and cell co‐cultures (yellow and red) on gold surfaces (green) covered by a self‐assembled monolayer (blue). Sequential masking of the surface with a polydimethylsiloxane membrane (gray) allows the controlled patterning of multiple cell lines (see picture).