A Two‐Photon Fluorescent Probe for Calcium Waves in Living Tissue | Zendy

Kim Hwan Myung | Zendy; Kim Bo Ra | Zendy; Hong Jin Hee | Zendy; Park JinSung | Zendy; Lee Kyoung J. | Zendy; Cho Bong Rae | Zendy

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A Two‐Photon Fluorescent Probe for Calcium Waves in Living Tissue

Author(s) -

Kim Hwan Myung,

Kim Bo Ra,

Hong Jin Hee,

Park JinSung,

Lee Kyoung J.,

Cho Bong Rae

Publication year - 2007

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.200701720

Subject(s) - photobleaching , fluorescence , calcium , fluorescence recovery after photobleaching , photon , two photon excitation microscopy , computer science , chemistry , nanotechnology , physics , optics , materials science , organic chemistry

Intracellular messaging : The novel two‐photon fluorescent probe ACa1 can visualize calcium waves in cells and living tissue for a long period of time and without any mistargeting problems (see picture). The probe is capable of monitoring the calcium waves at a depth of about 150 μm in living tissues for more than 1100 s and with no photobleaching artifacts.

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