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Intracellular Hydrogelation of Small Molecules Inhibits Bacterial Growth
Author(s) -
Yang Zhimou,
Liang Gaolin,
Guo Zufeng,
Guo Zhihong,
Xu Bing
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200701697
Subject(s) - intracellular , chemistry , small molecule , biophysics , microbiology and biotechnology , molecule , biochemistry , biology , organic chemistry
Control from within : Supramolecular hydrogelation to form nanostructures intracellularly (see picture) has been developed as a new methodology to control the fate of cells. Enzyme‐regulated self‐assembly of small molecules inside cells could lead to a new paradigm for managing cellular processes, understanding cellular functions, and developing new therapeutics through supramolecular chemistry.