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Asymmetric Total Synthesis of Pinnaic Acid
Author(s) -
Xu Shu,
Arimoto Hirokazu,
Uemura Daisuke
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200701581
Subject(s) - tandem , trimethylenemethane , key (lock) , stereospecificity , olefin metathesis , total synthesis , metathesis , olefin fiber , computer science , chemistry , stereochemistry , information retrieval , combinatorial chemistry , catalysis , organic chemistry , engineering , polymer , computer security , cycloaddition , polymerization , aerospace engineering
Pinned together : Asymmetric total synthesis of pinnaic acid was accomplished through a stereospecific route that features as key steps a Pd‐catalyzed trimethylenemethane (TMM) [3+2] cyclization, a four‐step tandem hydrogenation–cyclization, and cross‐olefin‐metathesis reactions (see scheme).