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An R ‐Selective Hydroxynitrile Lyase from Arabidopsis thaliana with an α/β‐Hydrolase Fold
Author(s) -
Andexer Jennifer,
von Langermann Jan,
Mell Annett,
Bocola Marco,
Kragl Udo,
Eggert Thorsten,
Pohl Martina
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200701455
Subject(s) - arabidopsis thaliana , lyase , chemistry , arabidopsis , enzyme , stereochemistry , hydrolase , biochemistry , gene , mutant
Folding and selectivity : The noncyanogenic plant Arabidopsis thaliana contains a new hydroxynitrile lyase, which was cloned and characterized. This enzyme is readily available form a recombinant source, has a broad range of substrates, and enantioselectively transforms aliphatic and aromatic aldehydes as well as ketones into the corresponding R ‐cyanohydrins.