Probing Local Structural Events in β‐Hairpin Unfolding with Transient Nonlinear Infrared Spectroscopy | Zendy

Smith Adam W. | Zendy; Tokmakoff Andrei | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Probing Local Structural Events in β‐Hairpin Unfolding with Transient Nonlinear Infrared Spectroscopy

Author(s) -

Smith Adam W.,

Tokmakoff Andrei

Publication year - 2007

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.200701172

Subject(s) - nonlinear system , folding (dsp implementation) , transient (computer programming) , jump , infrared , spectroscopy , infrared spectroscopy , chemical physics , content (measure theory) , temperature jump , physics , chemistry , crystallography , computer science , optics , mathematics , engineering , quantum mechanics , electrical engineering , mathematical analysis , operating system

Fast dynamics and kinky turns : The designed peptide PG12 forms a β‐hairpin stabilized by a D ‐Pro enhanced type‐II′ β turn. Through a combination of 13 C′ isotope labels and temperature‐jump nonlinear infrared spectroscopy local folding events were observed on a submicrosecond timescale, in which the turn region remains structured during the temperature jump, and midstrand region opens up on a 130‐ns timescale.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research