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Nickel‐Catalyzed Coupling of Arynes, Alkenes, and Boronic Acids: Dual Role of the Boronic Acid
Author(s) -
Jayanth Thiruvellore Thatai,
Cheng ChienHong
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200701063
Subject(s) - boronic acid , aryne , nickel , chemistry , catalysis , coupling (piping) , suzuki reaction , component (thermodynamics) , combinatorial chemistry , organic chemistry , materials science , palladium , metallurgy , physics , thermodynamics
Taking on a second job : Nickel catalyzes the three‐component coupling of arynes, alkenes, and boronic acids in very high yields under mild conditions. The boronic acid also acts as the proton source in this reaction. cod=1,5‐cyclooctadiene