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One Template, Multiple Rings: Controlled Iterative Addition of Macrocycles onto a Single Binding Site Rotaxane Thread
Author(s) -
Fuller AnneMarie L.,
Leigh David A.,
Lusby Paul J.
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200700933
Subject(s) - thread (computing) , rotaxane , computer science , chemistry , combinatorial chemistry , molecule , programming language , organic chemistry , supramolecular chemistry
One for all : The iteration of three simple steps—complexation, macrocyclization, and demetalation—enables the synthesis of multi‐ring rotaxanes with only one template site (see picture). This efficient and effective strategy enables both the number and the order in which macrocycles are assembled onto a thread to be controlled with unprecedented precision.