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Elucidation of Nonstatistical Dynamic Effects in the Cyclization of Enyne Allenes by Means of Kinetic Isotope Effects
Author(s) -
Schmittel Michael,
Vavilala Chandrasekhar,
Jaquet Ralph
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200700709
Subject(s) - kinetic isotope effect , enyne , kinetic energy , mechanism (biology) , chemistry , reaction mechanism , computational chemistry , isotope , physics , catalysis , nuclear physics , organic chemistry , deuterium , classical mechanics , quantum mechanics
In no man's land—a reaction without a classic mechanism : A series of enyne allenes follow neither the classical concerted nor stepwise mechanism but rather comply with dynamic nonstatistical laws. The computed potential energy surface (see figure) and experimental kinetic isotope effects indicate that dynamic effects operate before as well as after the transition state.