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Metal‐Catalyzed Copolymerization of Imines and CO: A Non‐Amino Acid Route to Polypeptides
Author(s) -
Sun Huailin,
Zhang Jian,
Liu Qiuhua,
Yu Lei,
Zhao Jiangyu
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200700646
Subject(s) - catalysis , cobalt , copolymer , carbon monoxide , chemistry , combinatorial chemistry , metal , path (computing) , organic chemistry , polymer chemistry , computer science , polymer , programming language
The path less taken : Copolymerization of imines and carbon monoxide has long been highly desirable as a route to synthesize polypeptides, but has been difficult to implement because of the lack of appropriate catalysts. This reaction has now been realized for the first time by using a simple cobalt catalyst (see scheme).