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Integration of a Self‐Assembling Protein Scaffold with Water‐Soluble Single‐Walled Carbon Nanotubes
Author(s) -
Holder Patrick G.,
Francis Matthew B.
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200700333
Subject(s) - bioconjugation , carbon nanotube , scaffold , ethylene glycol , pulmonary surfactant , scaffold protein , chemistry , tobacco mosaic virus , nanotechnology , pyrene , materials science , chemical engineering , polymer chemistry , organic chemistry , virus , biochemistry , medicine , signal transduction , engineering , virology , biomedical engineering , biology
Plastic tubing : The parallel alignment of single‐walled carbon nanotubes (NTs) with a self‐assembling biomolecular scaffold, the tobacco mosaic virus (TMV), is presented. A multifunctional polymeric surfactant brings together these two disparate components: The NTs are solubilized by a layer of poly(ethylene glycol) attached through a pyrene anchor, and the pendant alkoxyamine groups of the surfactant allow mild bioconjugation with ketone‐labeled proteins.