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A Pocket‐Sized Convective PCR Thermocycler
Author(s) -
Agrawal Nitin,
Hassan Yassin A.,
Ugaz Victor M.
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200700306
Subject(s) - polymerase chain reaction , computer science , simple (philosophy) , battery (electricity) , computational biology , multiplex , dna , power (physics) , electrical engineering , biology , physics , gene , genetics , engineering , thermodynamics , epistemology , philosophy
Is that a PCR in your pocket? An innovative thermocycling system is presented that harnesses natural convection to perform rapid multiplex and long‐target DNA amplification by the polymerase chain reaction (PCR). The design is inherently simple and consumes minimal electrical power, enabling a pocket‐sized battery‐powered device to be constructed at a cost of approximately US$10.