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Phenanthroline Ligands in Aryl Palladium Hydrazinato Complexes: Catalysts for Efficient Coupling of Azo Componds with Aryl Boronic Acids
Author(s) -
Muñiz Kilian,
Iglesias Alvaro
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200700288
Subject(s) - aryl , palladium , chemistry , combinatorial chemistry , amide , suzuki reaction , catalysis , phenanthroline , reactivity (psychology) , boronic acid , reductive elimination , organic chemistry , medicine , alkyl , alternative medicine , pathology
An easy couple: A new protocol for the synthesis of N‐arylated amides, based on a coupling between azodicarboxylates and aryl boronic acids, has been developed (see scheme). Palladadiaziridines serve as catalysts for this process and the key step consists of a reductive elimination from a hydrazinato palladium aryl intermediate that shows an unprecedented reactivity for this class of compounds in aryl–amide bond formation.