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Cover Picture: Artemisone—A Highly Active Antimalarial Drug of the Artemisinin Class (Angew. Chem. Int. Ed. 13/2006)
Author(s) -
Haynes Richard K.,
Fugmann Burkhard,
Stetter Jörg,
Rieckmann Karl,
Heilmann HansDietrich,
Chan HoWai,
Cheung ManKi,
Lam WaiLun,
Wong HoNing,
Croft Simon L.,
Vivas Livia,
Rattray Lauren,
Stewart Lindsay,
Peters Wallace,
Robinson Brian L.,
Edstein Michael D.,
Kotecka Barbara,
Kyle Dennis E.,
Beckermann Bernhard,
Gerisch Michael,
Radtke Martin,
Schmuck Gabriele,
Steinke Wolfram,
Wollborn Ute,
Schmeer Karl,
Römer Axel
Publication year - 2006
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200690045
Subject(s) - artemisinin , artemisia annua , malaria , cover (algebra) , traditional medicine , plasmodium falciparum , int , stereochemistry , chemistry , biology , medicine , computer science , engineering , immunology , mechanical engineering , operating system
Qing hao su , or artemisinin, is the active compound isolated from the herb Artemisia annua (qīng hāo) shown in the cover picture. The Chinese text shown describing its use in Chinese medicine dates back to 340 AD. Derivatives of artemisinin are currently used for the treatment of malaria. In their Communication on page 2082 ff., R. K. Haynes et al. describe the preparation and superior efficacy of the new derivative artemisone against the malaria parasite. (Chinese text verified by Prof. Chun‐Tao Che.)