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Cover Picture: Asymmetric Organocatalytic Henry Reaction (Angew. Chem. Int. Ed. 6/2006)
Author(s) -
Marcelli Tommaso,
van der Haas Richard N. S.,
van Maarseveen Jan H.,
Hiemstra Henk
Publication year - 2006
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200690021
Subject(s) - cinchona , nitroaldol reaction , thiourea , cinchona alkaloids , organocatalysis , chemistry , cover (algebra) , enantioselective synthesis , organic chemistry , bark (sound) , combinatorial chemistry , catalysis , forestry , geography , mechanical engineering , engineering
Alkaloids extracted from the Quinine tree bark are a privileged scaffold for the development of asymmetric organocatalysts. In their Communication on page 929 ff., H. Hiemstra and co‐workers describe a novel Cinchona ‐derived thiourea compound able to catalyze the Henry (nitroaldol) reaction of aromatic aldehydes with high enantioselectivities. The cover picture shows Cinchona pubescens (courtesy of Forest and Kim Starr, USA) and a typical Henry product.