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Stabilization of the Zwitterionic Structure of Proline by an Alkylammonium Ion in the Gas Phase
Author(s) -
Wu Ronghu,
McMahon Terry B.
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200605174
Subject(s) - methylamine , chemistry , protonation , ion , proline , gas phase , chemical physics , amino acid , phase (matter) , crystallography , inorganic chemistry , organic chemistry , biochemistry
Separate charges : Zwitterionic proline can be effectively stabilized by protonated methylamine in the gas phase (see calculated structure; C gray, H white, N blue, O red), as shown by accurate binding‐energy measurements and IR fingerprint spectra. These results imply that organic ions may provide an effective means of stabilizing the zwitterionic structures of amino acids, which are of fundamental importance in biological systems.