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Metalloenzyme‐Inspired Catalysis: Selective Oxidation of Primary Alcohols with an Iridium–Aminyl‐Radical Complex
Author(s) -
Königsmann Martin,
Donati Nicola,
Stein Daniel,
Schönberg Hartmut,
Harmer Jeffrey,
Sreekanth Anandaram,
Grützmacher Hansjörg
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200605170
Subject(s) - iridium , dehydrogenation , chemistry , catalysis , primary (astronomy) , photochemistry , alcohol oxidation , nitrogen , organic chemistry , physics , astronomy
A little goes a long way : An iridium–nitrogen‐radical complex is a highly active and selective catalyst for the dehydrogenation (oxidation) of primary alcohols to aldehydes in the presence of the oxidant benzoquinone (see simplified scheme). With only 0.01 mol % of the complex, turnover frequencies of up to 150 000 s −1 are reached.