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From the Alkyllithium Aggregate [{( n BuLi) 2 ⋅PMDTA} 2 ] to Lithiated PMDTA
Author(s) -
Strohmann Carsten,
Gessner Viktoria H.
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200605105
Subject(s) - deprotonation , chemistry , organic chemistry , ion
A commonly used deprotonation agent is the combination of n ‐butyllithium and N , N , N ′, N ′′, N ′′‐pentamethyldiethylenetriamine (PMDTA). The highly reactive aggregate [{( n BuLi) 2 ⋅PMDTA} 2 ] crystallizes out of a 2:1 mixture of n BuLi and PMDTA. The molecular structure provides insight into the significant influence of the n BuLi/PMDTA ratio on the course of some deprotonation reactions.