Microfluidic Control of Fluorescence Resonance Energy Transfer: Breaking the FRET Limit | Zendy

Zhang Chunyang | Zendy; Johnson Lawrence W. | Zendy

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Microfluidic Control of Fluorescence Resonance Energy Transfer: Breaking the FRET Limit

Author(s) -

Zhang Chunyang,

Johnson Lawrence W.

Publication year - 2007

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.200604861

Subject(s) - förster resonance energy transfer , microfluidics , nanosensor , detection limit , quantum dot , fluorescence , nanotechnology , limit (mathematics) , energy transfer , energy (signal processing) , chemistry , physics , materials science , chromatography , chemical physics , optics , quantum mechanics , mathematical analysis , mathematics

No empty FRET : The microfluidic control of fluorescence resonance energy transfer (FRET) has been demonstrated, and the FRET limit has been broken with a quantum‐dot (QD)‐based DNA nanosensor in a microfluidic flow. This nanosensor can detect long nucleic acids that have separation distances far beyond the range of FRET and whose detection is not feasible with conventional FRET‐based assays.

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