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Pentavalent Arsenic Can Bind to Biomolecules
Author(s) -
Raab Andrea,
Wright Stephen H.,
Jaspars Marcel,
Meharg Andrew A.,
Feldmann Jörg
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200604805
Subject(s) - arsenic , biomolecule , chemistry , sulfide , glutathione , reactivity (psychology) , environmental chemistry , biochemistry , enzyme , organic chemistry , medicine , alternative medicine , pathology
As biomolecules go : By identifying the dimethylarsinothioyl glutathione complex in arsenic‐exposed cabbage, it was shown that pentavalent arsenic can bind to biomolecules when it is activated by sulfide (see picture; As V purple, S yellow, O red, N blue). The result highlights that sulfide reactions may play a role in the reactivity of arsenic intermediates and the metabolic pathway of arsenic in organisms.