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Generation of Live‐Cell Microarrays by Means of DNA‐Directed Immobilization of Specific Cell‐Surface Ligands
Author(s) -
Schroeder Hendrik,
Ellinger Bernhard,
Becker Christian F. W.,
Waldmann Herbert,
Niemeyer Christof M.
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200604467
Subject(s) - dna microarray , dna , cell , computational biology , microarray , microbiology and biotechnology , biology , chemistry , gene , genetics , gene expression
Everything in its place : The DNA‐directed immobilization of specific cell‐surface ligands on a DNA microarray enables the generation of positionally encoded arrays of live cells. Such arrays can be used for fundamental research in molecular cell biology or as a screening platform in the area of drug development