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Reformatsky Reactions Meet Catalysis and Stereoselectivity
Author(s) -
Cozzi Pier Giorgio
Publication year - 2007
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200604344
Subject(s) - stereoselectivity , reformatsky reaction , catalysis , halide , chemistry , condensation reaction , condensation , organic chemistry , combinatorial chemistry , physics , thermodynamics
Classics reformed : The condensation reaction between aldehydes and ketones and α‐halocarbonyl compounds, known as the Reformatsky reaction, has undergone enormous development in recent times, including stereoselective and catalytic variants (see scheme, X=halide), The reliable, practical reaction makes it ideal for synthetic preparations on an industrial scale.